|
|
|
|
| LEADER |
00000cam a22000004a 4500 |
| 001 |
b1921561 |
| 003 |
CStclU |
| 005 |
20240627104143.0 |
| 008 |
080811t20092009njua bf 001 0 eng |
| 010 |
|
|
|a 2008035478
|
| 020 |
|
|
|a 9780470118030 (cloth)
|
| 020 |
|
|
|a 0470118032 (cloth)
|
| 035 |
|
|
|a (OCoLC)243818537
|
| 035 |
|
|
|a (OCoLC)243818537
|
| 040 |
|
|
|a DNLM/DLC
|c DLC
|d NLM
|d BTCTA
|d YDXCP
|d C#P
|d UtOrBLW
|
| 042 |
|
|
|a pcc
|
| 049 |
|
|
|a STAM
|
| 050 |
0 |
0 |
|a RM301.55
|b .D766 2009
|
| 245 |
0 |
0 |
|a Drug metabolism handbook :
|b concepts and applications /
|c edited by Ala F. Nassar, Paul F. Hollenberg, and JoAnn Scatina.
|
| 264 |
|
1 |
|a Hoboken, N.J. :
|b Wiley,
|c [2009]
|
| 264 |
|
4 |
|c ©2009
|
| 300 |
|
|
|a xvi, 1,041 pages :
|b illustrations ;
|c 25 cm
|
| 336 |
|
|
|a text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a unmediated
|b n
|2 rdamedia
|
| 338 |
|
|
|a volume
|b nc
|2 rdacarrier
|
| 505 |
0 |
|
|a Pt. 1: Introduction: 1. Historical perspective/Roberta S. King -- 2. Factors affecting metabolism/Roberta S. King -- 3. Biotransformations in drug metabolism/Roberta s. King -- 4. In Vivo metabolite kinetics/Zheng Yang -- 5. Pharmacogenetics and pharmacogenomics/Lilian G. Yengi -- 6. Introduction to drug transporters/Louis Leung and Aram Oganesian -- Pt. 2. Technologies for In Vitro and In Vivo studies: 7. Automated drug screening for ADMET properties/Melvin Reichman and Helen Gill -- 8. Mass spectrometry/Thomas R. Sharp -- 9. Approaches to performing metabolite elucidation: one key to success in drug discovery and development/Ala F. Nassar -- 10. Structural modifications of drug candidates: how useful are they in improving metabolic stability of new drugs? Pt. 1. Enhancing metabolic stability/Alaf F. Nassar -- 11. Structural modifications of drug candidates: how useful are they in improving PK parameters of new drugs? Pt. 2. Drug design strategies/Alaf F. Nassar -- 12. Minimizing the potential for dfrug bioactivation of drug candidates to success in clinical development/Alaf F. Nassar -- 13. Screening for reactive metabolites using genotoxicity arrays and enzyme/DNA biocolloids/James F. Rusling, ... [et al.] -- Pt. 3. Drug Interactions: 14. Enzyme inhibition/Paul F. Hollenberg -- 15. Evaluating and predicting human cytochrome P450 enzyme induction/Michael Sinz, ... [et al.] -- 16. An introduction to metabolic reaction phenotyping/Carl D. Davis and A. David Rodrigues -- 17. Nuclear receptor-mediated gene regulation in drug metabolism/Hongbing Wang and Wen Xie -- 18. Charaterization of Cytochrome P450 mechanism-based inhibition/Dan Rock and Larry C. Wienkers -- 19. Clinical drug-drug interactions/Sujal V. Deshmukh -- 20. Pharmaceutical excipients in drug-drug interaction/Chuan Chen and Abu J.M. Sadeque -- Pt. 4. Toxicity: 21. The role of drug metabolism in toxicity/Carl D. Davis and Umesh M. Hanumegowda -- 22. Allergic reactions to drugs/Mark P. Grillo -- 23. Chemical mechanisms in toxicology/Mark P. Grillo -- 24. Mechanisms of reproductive toxicity/Aileen F. Keating and Patricia B. Hoyer -- 25. An introduction to toxicogenomics/Aaron L. Vollrath and Christopher A. Bradfield -- 26. Role of bioactivation reactions in chemically induced nephrotoxicity/Laerence H. Lash -- Pt. 5. Regulatory perspectives: 27. Drug metabolism in regulatory guidances, clinical trials, and product labeling/Mark N. Milton.
|
| 504 |
|
|
|a Includes bibliographical references and index.
|
| 650 |
|
0 |
|a Drugs
|x Metabolism
|v Handbooks, manuals, etc.
|
| 650 |
|
7 |
|a Medication.
|2 homoit
|0 https://homosaurus.org/v3/homoit0001007
|
| 650 |
|
7 |
|a Therapies.
|2 homoit
|0 https://homosaurus.org/v3/homoit0001366
|
| 650 |
|
7 |
|a Drugs
|x Metabolism.
|2 fast
|0 (OCoLC)fst00898845
|
| 650 |
|
7 |
|a Drugs.
|2 fast
|0 (OCoLC)fst00898761
|
| 655 |
|
7 |
|a Handbooks and manuals.
|2 fast
|0 (OCoLC)fst01423877
|
| 700 |
1 |
|
|a Nassar, Ala F.
|0 http://id.loc.gov/authorities/names/n2008183481
|
| 700 |
1 |
|
|a Hollenberg, Paul F.
|0 http://id.loc.gov/authorities/names/n2008185013
|
| 700 |
1 |
|
|a Scatina, JoAnn.
|0 http://id.loc.gov/authorities/names/n2008185014
|
| 856 |
4 |
1 |
|z View Table of contents only
|u https://catdir.loc.gov/catdir/toc/ecip0825/2008035478.html
|t 0
|
| 907 |
|
|
|a .b19215617
|b 240629
|c 091113
|
| 998 |
|
|
|a umn
|b 100305
|c m
|d a
|e -
|f eng
|g nju
|h 0
|
| 918 |
|
|
|a .bckstg
|b 2016-12-01
|
| 999 |
f |
f |
|i bcffe944-92e3-5d50-a82c-75d57b7298f1
|s dd94f128-3ee3-52e7-816a-4efc2b38ea27
|t 0
|
| 952 |
f |
f |
|p Circulating
|a Santa Clara University
|b Santa Clara Main Campus
|c University Library
|d University Library ARS Main Stacks
|t 0
|e RM301.55 .D766 2009
|h Library of Congress classification
|i book
|m 35098108080048
|n c.1
|