Mechanisms of Lymphocyte Activation and Immune Regulation XI : B Cell Biology /

In recent years, major developments have been made in understanding various genetic and epigenetic regulatory processes that are critical for the generation of B cell repertoires. These include the role of chromatin regulation and nuclear organization in understating the IgH gene regulation. A role...

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Bibliographic Details
Other Authors: Gupta, Sudhir (Editor), Alt, Frederick (Editor), Cooper, Max (Editor), Melchers, Fritz (Editor), Rajewsky, K., 1936- (Editor)
Format: Electronic eBook
Language:English
Published: Boston, MA : Springer US, 2007.
Series:Advances in experimental medicine and biology ; 596.
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Online Access:Connect to this title online
Table of Contents:
  • Regulation and Function of the E2A Proteins in B Cell Development
  • Multiple Roles for Blimp-1 in B and T Lymphocytes
  • Memory B Cell Evolution: B Cell Biology
  • BCR-linked Factors in Developmental Fate Decisions
  • Gene Regulatory Networks that Orchestrate the Development of B Lymphocyte Precursors
  • Rules for the Rearrangement Events at the L Chain Gene Loci of the Mouse
  • Regulation of AID Function In Vivo
  • Targeting of AID to Immunoglobulin Genes
  • Targeting AID to the Ig Genes
  • DNA Replication to Aid Somatic Hypermutation
  • Regulation of Activation Induced Deaminase via Phosphorylation
  • Modulation of MHC Class II Signal Transduction by CD19
  • Role of NFUP?B Signaling in Normal and Malignant B Cell Development
  • Fc Receptor–like Proteins (FCRL): Immunomodulators of B Cell Function
  • Tolerance Mechanisms in the Late Phase of the Antibody Response
  • Role of RS/?DE in B Cell Receptor Editing
  • The Regulation of Receptor Editing
  • B Cell Hyporesponsiveness and Autoimmunity: A New Paradigm.