Aging and Age-Related Disorders

Aging and Age-Related Disorders /

Features that characterize the aging process include the gradual accumulation of cell damage after prolonged exposure to oxidative and inflammatory events over a lifetime. In addition to the accretion of lesions, the intrinsic levels of pro-oxidant and aberrant immune responses are elevated with age...

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Bibliographic Details
Other Authors: Bondy, Stephen C. (Editor), Maiese, Kenneth, 1958- (Editor)
Format: Electronic eBook
Language:English
Published: Totowa, NJ : Humana Press : Imprint: Humana Press, 2010.
Series:Oxidative stress in applied basic research and clinical practice.
Subjects:
Medicine.
Human physiology.
Geriatrics.
Cytology.
Oxidative stress.
Biomedicine.
Human Physiology.
Oxidative Stress.
Geriatrics/Gerontology.
Cell Biology.
Online Access:Connect to this title online
Table of Contents:
  • General Aspects of Aging
  • Protein Redox-Regulation Mechanisms in Aging
  • Nitrosative Stress in Aging – Its Importance and Biological Implications in NF-?B Signaling
  • Intervention with Multiple Micronutrients Including Dietary and Endogenous Antioxidants for Healthy Aging
  • Advanced Glycation End Products, RAGE, and Aging
  • Sirtuins and Mammalian Aging
  • Estrogenic Modulation of Longevity by Induction of Antioxidant Enzymes
  • Mitochondrial Respiratory Function Decline in Aging and Life-Span Extension by Caloric Restriction
  • Methylglyoxal, Oxidative Stress, and Aging
  • The Cardiovascular System
  • Novel Strategies for Neurovascular Longevity During Aging
  • Oxidative Stress in Vascular Disease
  • The Role of Mitochondrial Reactive Oxygen Species Formation for Age-Induced Vascular Dysfunction
  • Aging, Oxidative Stress, and Cardiovascular Disorders
  • Oxidative Stress, Aging, and Cardiovascular Disease
  • Antioxidation in Prevention of Cardiovascular Diseases – An Effect of Polyphenols
  • Vascular Aging and Oxidative Stress: Hormesis and Adaptive Cellular Pathways
  • Role of Oxidative Stress in Mediating Elevated Blood Pressure with Aging
  • The Nervous System
  • Melatonin, Oxidative Stress, and the Aging Brain
  • The SAM Strain of Mice, a Higher Oxidative Stress, Age-Dependent Degenerative Disease, and Senescence Acceleration Model
  • Antioxidants Combined with Behavioral Enrichment Can Slow Brain Aging
  • Role of Nitric Oxide in Neurodegeneration and Vulnerability of Neuronal Cells to Nitric Oxide Metabolites and Reactive Oxygen Species
  • Free Radical–Mediated Damage to Brain in Alzheimer’s Disease: Role of Acrolein and Preclinical Promise of Antioxidant Polyphenols
  • An Epigenetic Model for Susceptibility to Oxidative DNA Damage in the Aging Brain and Alzheimer’s Disease.

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